2020
Pandey, S., Banks, K.M., Kumar, R., Kuo, A., Wen, D., Hla, T, and Evans, T. (2020). Sphingosine Kinases Protect Murine ESCs from Sphingosine-induced Cell Cycle Arrest. Stem Cells. In Press.
Pandey, S., Banks, K.M., Kumar, R., Kuo, A., Wen, D., Hla, T, and Evans, T. (2020). Sphingosine Kinases Protect Murine ESCs from Sphingosine-induced Cell Cycle Arrest. Stem Cells. In Press.
2019
Lan, Y., Pan, H., Li, C., Banks, K.M., Sam, J., Ding, B., Elemento, O., Goll, M. and Evans, T. TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis. (2019). Cell Reports. 26: 720-734.
Fernando, T., Marullo, R., Pera, B., Phillip, J., Yang, S.N., Lundell-Smith, G., Torregroza, I., Ahn, H., Evans, T., Györffy, B., Prive, G.G., Hirano, M., Melnick, A., and Cerchietti, L. (2019). BCL6 Evolved to Enable Stress Tolerance in Vertebrates and is Broadly Required by Cancer Cells to Adapt to Stress. Cancer Discov. 9: 662-697.
Li, H., Saucedo-Cuevas, L., Yuan, L., Ross, D., Johansen, A., Sands, D., Stanley, V., Guemez-Gamboa, A., Gregor, A., Evans, T., Chen, S., Tan, L., Molina, H., Sheets, N., Shiryaev, S.A., Terskikh, A.V., Gladfelter, A.S., Shresta, S., Xu, Z., Gleeson, J.G. (2019). Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors. Neuron. 101: 1-10.
Badieyan, Z.S. and Evans, T. (2019). Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering. Stem Cells Trans. Med. 8: 833-843.
Cook, B., Rafiq, R., Lee, H., Banks, K.M., El-Debs, M., Chiaravalli, J., Glickman, J.F., Das, B.C., Chen, S., Evans, T. (2019). Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-beta. Cell Chem. Biol. 26: 1-10.
Li, Q.V., Dixon, G., Verma, N., Rosen, B.P., Gordillo, M., Xu, C., Wang, Q., Soh, C.-L., Yang, D., Crespo, M., Luo, R., Shukla, A., Xiang, Q., Dundar, F., Zumbo, P., Witkin, M., Koche, R., Betel, D., Chen, S., Massague, J., Garippa, R., Evans, T., Beer, M.A., Huangfu, D. (2019). Genome-Scale Screens Uncover JNK/JUN Signaling as a Key Barrier from Pluripotency to Human Endoderm Differentiation. Nature Genetics. 51: 999-1010.
Kumar, R. and Evans, T. (2019). The Cytosine Deaminase AICDA Regulates FGF/ERK Signaling to Achieve the Naïve Pluripotent State During Reprogramming. Stem Cells. 37: 1003-1017.
Jaffré, F., Miller, C.L., Schanzer, A., Evans, T., Roberts, A.E., Hahn, A., Kontaridis, M.I. (2019). Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome. Circulation. 140: 207-224.
Tsai, S.-Y., Ghazizadeh, Z., Wang, H.-J., Amin, S., Ortega, F.A., Badieyan, Z.S., Hsu, Z.-T., Gordillo, M., Kumar, R., Christini, D.J., Evans*, T. and Chen*, S. (2019). A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity. Cardiovasc. Res. cvz148, https://doi.org/10.1093/cvr/cvz148.
Lee, H. and Evans, T. (2019). TMEM88 Inhibits Wnt Signaling by Promoting Wnt Signalosome Localization to Multivesicular Bodies. iScience. 19: 267-280.
Lan, Y. and Evans, T. (2019). Epigenetic Regulation of Cardiac Development and Disease through DNA Methylation. J. Life Sciences. 1: 1-10.
Tan, L., Lacko, L.A., Zhou, T., Tomoiaga, D., Hurtado, R., Zhang, T., Sevilla, A., Zhong, A., Mason, C., Noggle, S., Evans, T., Stuhlmann, H., Schwartz, R.E., Chen, S. (2019). Pre- and Peri-implantation Zika Virus Infection Impairs Fetal Development by Targeting Trophectoderm Cells. Nature Comm. 10: 4155. Doi: 10.1038/s41467-019-12063-2.
Lan, Y., Pan, H., Li, C., Banks, K.M., Sam, J., Ding, B., Elemento, O., Goll, M. and Evans, T. TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis. (2019). Cell Reports. 26: 720-734.
Fernando, T., Marullo, R., Pera, B., Phillip, J., Yang, S.N., Lundell-Smith, G., Torregroza, I., Ahn, H., Evans, T., Györffy, B., Prive, G.G., Hirano, M., Melnick, A., and Cerchietti, L. (2019). BCL6 Evolved to Enable Stress Tolerance in Vertebrates and is Broadly Required by Cancer Cells to Adapt to Stress. Cancer Discov. 9: 662-697.
Li, H., Saucedo-Cuevas, L., Yuan, L., Ross, D., Johansen, A., Sands, D., Stanley, V., Guemez-Gamboa, A., Gregor, A., Evans, T., Chen, S., Tan, L., Molina, H., Sheets, N., Shiryaev, S.A., Terskikh, A.V., Gladfelter, A.S., Shresta, S., Xu, Z., Gleeson, J.G. (2019). Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors. Neuron. 101: 1-10.
Badieyan, Z.S. and Evans, T. (2019). Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering. Stem Cells Trans. Med. 8: 833-843.
Cook, B., Rafiq, R., Lee, H., Banks, K.M., El-Debs, M., Chiaravalli, J., Glickman, J.F., Das, B.C., Chen, S., Evans, T. (2019). Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-beta. Cell Chem. Biol. 26: 1-10.
Li, Q.V., Dixon, G., Verma, N., Rosen, B.P., Gordillo, M., Xu, C., Wang, Q., Soh, C.-L., Yang, D., Crespo, M., Luo, R., Shukla, A., Xiang, Q., Dundar, F., Zumbo, P., Witkin, M., Koche, R., Betel, D., Chen, S., Massague, J., Garippa, R., Evans, T., Beer, M.A., Huangfu, D. (2019). Genome-Scale Screens Uncover JNK/JUN Signaling as a Key Barrier from Pluripotency to Human Endoderm Differentiation. Nature Genetics. 51: 999-1010.
Kumar, R. and Evans, T. (2019). The Cytosine Deaminase AICDA Regulates FGF/ERK Signaling to Achieve the Naïve Pluripotent State During Reprogramming. Stem Cells. 37: 1003-1017.
Jaffré, F., Miller, C.L., Schanzer, A., Evans, T., Roberts, A.E., Hahn, A., Kontaridis, M.I. (2019). Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome. Circulation. 140: 207-224.
Tsai, S.-Y., Ghazizadeh, Z., Wang, H.-J., Amin, S., Ortega, F.A., Badieyan, Z.S., Hsu, Z.-T., Gordillo, M., Kumar, R., Christini, D.J., Evans*, T. and Chen*, S. (2019). A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity. Cardiovasc. Res. cvz148, https://doi.org/10.1093/cvr/cvz148.
Lee, H. and Evans, T. (2019). TMEM88 Inhibits Wnt Signaling by Promoting Wnt Signalosome Localization to Multivesicular Bodies. iScience. 19: 267-280.
Lan, Y. and Evans, T. (2019). Epigenetic Regulation of Cardiac Development and Disease through DNA Methylation. J. Life Sciences. 1: 1-10.
Tan, L., Lacko, L.A., Zhou, T., Tomoiaga, D., Hurtado, R., Zhang, T., Sevilla, A., Zhong, A., Mason, C., Noggle, S., Evans, T., Stuhlmann, H., Schwartz, R.E., Chen, S. (2019). Pre- and Peri-implantation Zika Virus Infection Impairs Fetal Development by Targeting Trophectoderm Cells. Nature Comm. 10: 4155. Doi: 10.1038/s41467-019-12063-2.
2018
Surya SL, Long MJC, Urul DA, Zhao Y, Mercer EJ, EIsaid IM, Evans T, Aye Y. (2018). Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged
Reactive Electrophilic Species (RES) Sensor. ACS Chem. Biol. 13: 1824-1831. www.ncbi.nlm.nih.gov/pubmed/29397684
Mercer EJ, Lin YF, Cohen-Gould L, Evans T. (2018). Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis. Dev. Biol. 435: 41-55.
Ghazizadeh, Z., Fattahi, F., Mirzaei, M., Chae, S., Byun, K., Tabar, M.S., Ahmad, S.T., Mirshahvaladi, S., Shabani, P., Fonoudi, H., Baharvand, H., Aghdami, N., Evans, T., Lee, B., Salekdeh, G.H. (2018). Prospective Isolation of ISL1+ Cardiac Progenitors from human ESCs for Myocardial Infarction Therapy. Stem Cell Reports. 10: 848-859.
Amin, S., Cook, B., Zhou, T., Ghazizadeh, Z., Lis, R., Zhang, T., Khalaj, M., Crespo, M., Perera, M., Xiang, J.Z., Zhu, Z., Tomishima, M., Evans, T., Huangfu, D., and Chen, S. (2018). Discovery of a Drug Candidate for GLIS3-Associated Diabetes. Nature Comm.9: 2681.
Zhou, T., Kim, T.W., Chong, C.N., Tan, L., Amin, S., Badieyan, Z., Mukherjee, S., Ghazizadeh, Z.,Zeng, H., Guo, M., Crespo, M.,Zhang, T., Kenyon, R., Robinson, C.L.,Apostolou, E.,Wang, H., Xiang, J.Z., Evans, T., Studer, L., Chen. S. (2018). A hPSC-based Platform to Discover Gene-Environment Interactions that Impact Human β -Cell and Dopamine Neuron Survival. Nature Comm.9: 4815.
Surya SL, Long MJC, Urul DA, Zhao Y, Mercer EJ, EIsaid IM, Evans T, Aye Y. (2018). Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged
Reactive Electrophilic Species (RES) Sensor. ACS Chem. Biol. 13: 1824-1831. www.ncbi.nlm.nih.gov/pubmed/29397684
Mercer EJ, Lin YF, Cohen-Gould L, Evans T. (2018). Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis. Dev. Biol. 435: 41-55.
Ghazizadeh, Z., Fattahi, F., Mirzaei, M., Chae, S., Byun, K., Tabar, M.S., Ahmad, S.T., Mirshahvaladi, S., Shabani, P., Fonoudi, H., Baharvand, H., Aghdami, N., Evans, T., Lee, B., Salekdeh, G.H. (2018). Prospective Isolation of ISL1+ Cardiac Progenitors from human ESCs for Myocardial Infarction Therapy. Stem Cell Reports. 10: 848-859.
Amin, S., Cook, B., Zhou, T., Ghazizadeh, Z., Lis, R., Zhang, T., Khalaj, M., Crespo, M., Perera, M., Xiang, J.Z., Zhu, Z., Tomishima, M., Evans, T., Huangfu, D., and Chen, S. (2018). Discovery of a Drug Candidate for GLIS3-Associated Diabetes. Nature Comm.9: 2681.
Zhou, T., Kim, T.W., Chong, C.N., Tan, L., Amin, S., Badieyan, Z., Mukherjee, S., Ghazizadeh, Z.,Zeng, H., Guo, M., Crespo, M.,Zhang, T., Kenyon, R., Robinson, C.L.,Apostolou, E.,Wang, H., Xiang, J.Z., Evans, T., Studer, L., Chen. S. (2018). A hPSC-based Platform to Discover Gene-Environment Interactions that Impact Human β -Cell and Dopamine Neuron Survival. Nature Comm.9: 4815.
2017
Guo M, Zhang T, Dong X, Xiang JZ, Lei M, Evans T, Graumann J, Chen S. (2017). Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E .Cell Reports 19: 1512-1521. www.ncbi.nlm.nih.gov/pubmed/28538172
Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D. (2017). Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell 20: 675-688. www.ncbi.nlm.nih.gov/pubmed/28196600
Tsai SY, Chen S, Evans T. Efficient Generation of Cardiac Purkinje-like Cells from Embryonic Stem Cells by Activating cAMP Signaling. Curr. Protoc. Stem Cell Biol. 40: 1F.16.1-1F.16.13 www.ncbi.nlm.nih.gov/pubmed/28152183
Ghazizadeh, Z., Kao, D.-I., Amin, S., Cook, B., Rao, S., Zhang, T., Xiang, Z., Kenyon, R., Kaymakcalan, O., Liu, C., Evans, T., and Chen, S. (2017). ROCKII Inhibition Promotes the Maturation of Human Pancreatic Beta-like Cells. Nature Comm. 8: 298. 10.1038/s41467-017-00129-y
Crespo, M., Vilar, E., Tsai, S.-Y., Chang, K., Amin, S., Srinivasan, T., Zhang, T., Pipalia, N.H., Chen, H.J., Xiang, J.Z., Maxfield, F.R., Lipkin, S., Evans*, T., and Chen*, S. (2017). Colonic Organoids Derived from Human Pluripotent Stem Cells for Modeling Colorectal Cancer and Drug Discovery. Nature Med. 23: 878-884. 10.1038/nm.4355
Zhou, T., Tan, L., Cederquist, G.Y., Fan, Y., Hartley, B.J., Mukherjee, S., Tomishima, M., Brennand, K.J., Zhang, Q., Schwartz, R.E., Evans, T., Studer, L., and Chen, S. (2017). High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain. Cell Stem Cell. 21: 274-283. 10.1016/j.stem.2017.06.017
Mendelson, K., Pandey, S., Hisano, Y., Carellini, F., Das, B., Hla, T., and Evans, T. (2017). The Ceramide Synthase 2b Gene Mediates Genomic Sensing and Regulation of Sphingosine Levels During Zebrafish Embryogenesis. eLife. 6: pii: e21992. 10.7554/eLife.21992
Tsai, S.-Y., Chen, S., and Evans, T. (2017). Efficient Generation of Cardiac Purkinje-like Cells from Embryonic Stem Cells by Activating cAMP Signaling. Curr. Protoc. Stem Cell Biol. 40: 1F.16.1-1F.16.13.
Mercer, E.J. and Evans, T. (2017). Congenital Heart Disease in a Dish: Progress Toward Understanding Patient-Specific Mutations. J. Thor. Dis. 9: E510-E513.
Guo M, Zhang T, Dong X, Xiang JZ, Lei M, Evans T, Graumann J, Chen S. (2017). Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E .Cell Reports 19: 1512-1521. www.ncbi.nlm.nih.gov/pubmed/28538172
Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D. (2017). Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell 20: 675-688. www.ncbi.nlm.nih.gov/pubmed/28196600
Tsai SY, Chen S, Evans T. Efficient Generation of Cardiac Purkinje-like Cells from Embryonic Stem Cells by Activating cAMP Signaling. Curr. Protoc. Stem Cell Biol. 40: 1F.16.1-1F.16.13 www.ncbi.nlm.nih.gov/pubmed/28152183
Ghazizadeh, Z., Kao, D.-I., Amin, S., Cook, B., Rao, S., Zhang, T., Xiang, Z., Kenyon, R., Kaymakcalan, O., Liu, C., Evans, T., and Chen, S. (2017). ROCKII Inhibition Promotes the Maturation of Human Pancreatic Beta-like Cells. Nature Comm. 8: 298. 10.1038/s41467-017-00129-y
Crespo, M., Vilar, E., Tsai, S.-Y., Chang, K., Amin, S., Srinivasan, T., Zhang, T., Pipalia, N.H., Chen, H.J., Xiang, J.Z., Maxfield, F.R., Lipkin, S., Evans*, T., and Chen*, S. (2017). Colonic Organoids Derived from Human Pluripotent Stem Cells for Modeling Colorectal Cancer and Drug Discovery. Nature Med. 23: 878-884. 10.1038/nm.4355
Zhou, T., Tan, L., Cederquist, G.Y., Fan, Y., Hartley, B.J., Mukherjee, S., Tomishima, M., Brennand, K.J., Zhang, Q., Schwartz, R.E., Evans, T., Studer, L., and Chen, S. (2017). High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain. Cell Stem Cell. 21: 274-283. 10.1016/j.stem.2017.06.017
Mendelson, K., Pandey, S., Hisano, Y., Carellini, F., Das, B., Hla, T., and Evans, T. (2017). The Ceramide Synthase 2b Gene Mediates Genomic Sensing and Regulation of Sphingosine Levels During Zebrafish Embryogenesis. eLife. 6: pii: e21992. 10.7554/eLife.21992
Tsai, S.-Y., Chen, S., and Evans, T. (2017). Efficient Generation of Cardiac Purkinje-like Cells from Embryonic Stem Cells by Activating cAMP Signaling. Curr. Protoc. Stem Cell Biol. 40: 1F.16.1-1F.16.13.
Mercer, E.J. and Evans, T. (2017). Congenital Heart Disease in a Dish: Progress Toward Understanding Patient-Specific Mutations. J. Thor. Dis. 9: E510-E513.
2016
Zeng H, Guo M, Zhou T, Tan L, Chong CN, Zhang T, Dong X, Xiang JZ, Yu AS, Yue L, Qi Q, Evans T, Graumann J, Chen S. An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery. Cell Stem Cell19: 326-340. www.ncbi.nlm.nih.gov/pubmed/27524441
Simsek, S., Zhou, T., Robinson, C.L., Tsai, S.-Y., Lin, X., Hon, J., Evans, T., and Chen, S. (2016). Modeling Cystic Fibrosis using PSC-derived Human Pancreatic Ductal Epithelial Cells. Stem Cells Regen. Med. 5: 572-579 www.ncbi.nlm.nih.gov/pubmed/27034411
Feng, L., Cook, B.D., Tsai, S.-Y., Zhou, T., LaFlamme, B., Evans*, T., and Chen*, S. (2016). Discovery of a Small Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation.Cell Reports15: 2063-2075. www.ncbi.nlm.nih.gov/pubmed/27210748
Zeng H, Guo M, Zhou T, Tan L, Chong CN, Zhang T, Dong X, Xiang JZ, Yu AS, Yue L, Qi Q, Evans T, Graumann J, Chen S. An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery. Cell Stem Cell19: 326-340. www.ncbi.nlm.nih.gov/pubmed/27524441
Simsek, S., Zhou, T., Robinson, C.L., Tsai, S.-Y., Lin, X., Hon, J., Evans, T., and Chen, S. (2016). Modeling Cystic Fibrosis using PSC-derived Human Pancreatic Ductal Epithelial Cells. Stem Cells Regen. Med. 5: 572-579 www.ncbi.nlm.nih.gov/pubmed/27034411
Feng, L., Cook, B.D., Tsai, S.-Y., Zhou, T., LaFlamme, B., Evans*, T., and Chen*, S. (2016). Discovery of a Small Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation.Cell Reports15: 2063-2075. www.ncbi.nlm.nih.gov/pubmed/27210748
2015
Gordillo, M., Evans, T., and Gouon-Evans, V. (2015). Orchestrating Liver Development. Development. 142(12):2094-2108
Tsai SY., Maass K., Lu J., Fishman G.I., Chen S., Evans T. (2015). Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling. Stem Cell Reports. 4(6):1089-1102
Mendelson K., Lan Y., Hla T., Evans T. (2015). Maternal or zygotic sphingosine kinase is required to regulate zebrafish cardiogenesis. Dev Dyn. 244(8):948-954
Li C., Lan Y., Schwartz-Orbach L., Korol E., Tahiliani M., Evans T., Goll M.G. (2015). Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell Rep. 12(7):1133-1143
Sundaravel, S., Duggan, R., Bhagat, T.D., Ebenezer, D., Liu, H., Yu, Y., Bartenstein, M., Unnikrishnan, M., Karmakar, S., Liu, T.-C., Torregroza, I., Quenon, T., Anastasi, J., McGraw, K., Pellagatti, A., Boultwood, J., Yajnik, V., Artz, A., Le Beau, M.M., Steidl, U., List, A., Evans*, T., Verma*, A., and Wickrema*, A. (2015). Reduced DOCK4 Expression Leads to Erythroid Dysplasia in Myelodysplastic Syndromes. Proc. Natl. Acad. Sci. USA. 112: E6359-6368
Kumar, R. and Evans, T. (2015). Haematopoiesis (version 4). Encyclopedia of Life Sciences, Nature Publishing Group, London. www.els.com.
Tsai SY., Maass K., Lu J., Fishman G.I., Chen S., Evans T. (2015). Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling. Stem Cell Reports. 4(6):1089-1102
Mendelson K., Lan Y., Hla T., Evans T. (2015). Maternal or zygotic sphingosine kinase is required to regulate zebrafish cardiogenesis. Dev Dyn. 244(8):948-954
Li C., Lan Y., Schwartz-Orbach L., Korol E., Tahiliani M., Evans T., Goll M.G. (2015). Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell Rep. 12(7):1133-1143
Sundaravel, S., Duggan, R., Bhagat, T.D., Ebenezer, D., Liu, H., Yu, Y., Bartenstein, M., Unnikrishnan, M., Karmakar, S., Liu, T.-C., Torregroza, I., Quenon, T., Anastasi, J., McGraw, K., Pellagatti, A., Boultwood, J., Yajnik, V., Artz, A., Le Beau, M.M., Steidl, U., List, A., Evans*, T., Verma*, A., and Wickrema*, A. (2015). Reduced DOCK4 Expression Leads to Erythroid Dysplasia in Myelodysplastic Syndromes. Proc. Natl. Acad. Sci. USA. 112: E6359-6368
Kumar, R. and Evans, T. (2015). Haematopoiesis (version 4). Encyclopedia of Life Sciences, Nature Publishing Group, London. www.els.com.
2014
Mendelson, K., Evans, T., and Hla, T. (2014). Sphingosine-1-phosphate Signaling in Development. Development. 141: 5-9.
Lundquist, M.R., Storaska, A., Liu, T.-C., Larsen, S.D., Evans, T., Neubig, R.R., and Jaffrey, S. (2014). Redox Modification of Nuclear Actin by MICAL-2 Regulates SRF Signaling. Cell. 156: 563-576.
Li, X., Lu, Y.-C., Dai, K., Torregroza, I., Hla*, T., and Evans*, T. (2014). Elavl1a Regulates Zebrafish Erythropoiesis via Post-transcriptional Control of gata1. Blood. 123: 1384-1392.
Das, B.C., Thapa, P., Karki, R., Das, S., Mahapatra, S., Liu, T.-C., Torregroza, I., Wallace, D.P., Kambhampati, S., Van Veldhuizen, P., Verma, A., Ray, S.K., and Evans, T. (2014). Retinoic Acid Signaling Pathways in Development and Diseases. Bioorg. Med. Chem. 22: 673-683.
Kleiman, D.A., Beninato T., Sultan, S., Crowley, M.J., Finnerty, B., Kumar, R., Panarelli, N.C., Liu, Y.-F., Lieberman, M.D., Seandel, M., Evans, T., Elemento, O., Zarnegar, R., and Fahey, T.J.III. (2014). Silencing of UCHL1 by CpG Promoter Hypermethylation is Associated With Metastatic Gastroenteropancreatic Well-Differentiated Neuroendocrine (Carcinoid) Tumors. Annals of Surg. Oncol. Suppl 4: 672-679.
Kumar, R., DiMenna, L.J., Chaudhuri, J., and Evans, T. (2014). Biological Function of Activation-Induced Cytidine Deaminase (AID). Biomed. J. 37: 269-283.
Kumar, R. and Evans, T. (2014). Control of Epigenetic Memory and Pluripotency by DNA Methylation. Cell Biology: Research & Therapy. S1. doi:10.4172/2324-9293.S1-002.
Cook, B.D. and Evans, T. (2014). BMP Signaling Balances Murine Myeloid Potential Through SMAD-independent p38MAPK and NOTCH Pathways. Blood. 124: 393-402.
Lundquist, M.R., Storaska, A., Liu, T.-C., Larsen, S.D., Evans, T., Neubig, R.R., and Jaffrey, S. (2014). Redox Modification of Nuclear Actin by MICAL-2 Regulates SRF Signaling. Cell. 156: 563-576.
Li, X., Lu, Y.-C., Dai, K., Torregroza, I., Hla*, T., and Evans*, T. (2014). Elavl1a Regulates Zebrafish Erythropoiesis via Post-transcriptional Control of gata1. Blood. 123: 1384-1392.
Das, B.C., Thapa, P., Karki, R., Das, S., Mahapatra, S., Liu, T.-C., Torregroza, I., Wallace, D.P., Kambhampati, S., Van Veldhuizen, P., Verma, A., Ray, S.K., and Evans, T. (2014). Retinoic Acid Signaling Pathways in Development and Diseases. Bioorg. Med. Chem. 22: 673-683.
Kleiman, D.A., Beninato T., Sultan, S., Crowley, M.J., Finnerty, B., Kumar, R., Panarelli, N.C., Liu, Y.-F., Lieberman, M.D., Seandel, M., Evans, T., Elemento, O., Zarnegar, R., and Fahey, T.J.III. (2014). Silencing of UCHL1 by CpG Promoter Hypermethylation is Associated With Metastatic Gastroenteropancreatic Well-Differentiated Neuroendocrine (Carcinoid) Tumors. Annals of Surg. Oncol. Suppl 4: 672-679.
Kumar, R., DiMenna, L.J., Chaudhuri, J., and Evans, T. (2014). Biological Function of Activation-Induced Cytidine Deaminase (AID). Biomed. J. 37: 269-283.
Kumar, R. and Evans, T. (2014). Control of Epigenetic Memory and Pluripotency by DNA Methylation. Cell Biology: Research & Therapy. S1. doi:10.4172/2324-9293.S1-002.
Cook, B.D. and Evans, T. (2014). BMP Signaling Balances Murine Myeloid Potential Through SMAD-independent p38MAPK and NOTCH Pathways. Blood. 124: 393-402.
2013
Das B.C., McCormick L., Thapa P., Karki R., Evans T. (2013). Use of zebrafish in chemical biology and drug discovery. (2013) Future Med. Chem. 5(17):2103-16
Das B.C., Tang X.Y., Rogler P., Evans T. (2013). Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs. Tetrahedron Lett. 53(31):3947-3950.
Chang, S.-H., Lu, Y.-C., Li, X., Hsieh, W.-Y., Xiong, Y., Ghosh, M., Evans, T., Elemento, O., and Hla, T. (2013). The RNA-binding protein HuR antagonizes miR-200b repression to regulate VEGF-A expression and angiogenesis . J. Biol. Chem. 288: 4908-4921.
Mendelson, K., Zygmunt, T., Torres-Vazquez, J., Evans*, T., and Hla*, T. (2013). Sphingosine-1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning. J. Biol. Chem. 288: 2143-2156.
Berman, N., Lectura, M., Thurman, J., Raff, A., Melamed, M.L., Reinecke, J., Quan, Z., Evans, T., Meyer, T.W., and Hostetter, T.H. (2013). A Zebrafish Model for Uremic Toxicity: Role of the Complement Pathway. Blood Purification. 35:265-269.
Turbendian, H.K., Gordillo, M., Tsai, S.-Y., Lu, J., Kang, G., Liu, T.-C., Tang, A., Liu, S., Fishman, G.I., and Evans, T. (2013). GATA factors efficiently direct cardiac fate from ESCs. Development. 140: 1639-1644.
Goldman, O., Han, S., Sourrisseau, M., Dziedzic, N., Hamou, W., Corneo, B., D'Souza, S., Sato, T., Kotton, D.N., Bissig, K.-K., Kalir, T., Jacobs, A., Evans, T., Evans, M.J., and Gouon-Evans, V. (2013). KDR (VEGFR2) identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell. 12: 748-760.
Choudhuri, A., Maitra, U., and Evans, T. (2013). Translation initiation factor eIF3h targets specific transcipts to polysomes during embryogenesis. Proc. Natl. Acad. Sci. USA. 110: 9818-9823.
Gupta, V., Gemberling, M., Karra, R., Rosenfeld, G.E., Evans, T., and Poss, K.D. (2013). An Injury-Responsive Gata4 Program Shapes the Zebrafish Cardiac Ventricle. Current Biology. 23: 1221-1227.
Kumar, R., DiMenna, L., Schrode, N., Liu, T.-C., Franck, P., Munoz-Descalzo, S., Hadjantonakis, A.-K, Zarrin, A.A., Chaudhuri, J., Elemento, O., and Evans, T. (2013). AID Stabilizes Stem Cell Phenotype by Removing Epigenetic Memory of Pluripotency Genes. Nature. 500: 89-92.
Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T. (2013). Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis. Dev. Biol. 381: 389-400.
Novikov, N. and Evans, T. (2013). Tmem88a Mediates GATA-dependent Specification of Cardiomyocyte Progenitors by Restricting WNT Signaling. Development. 40: 3787-3798.
Das B.C., Tang X.Y., Rogler P., Evans T. (2013). Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs. Tetrahedron Lett. 53(31):3947-3950.
Chang, S.-H., Lu, Y.-C., Li, X., Hsieh, W.-Y., Xiong, Y., Ghosh, M., Evans, T., Elemento, O., and Hla, T. (2013). The RNA-binding protein HuR antagonizes miR-200b repression to regulate VEGF-A expression and angiogenesis . J. Biol. Chem. 288: 4908-4921.
Mendelson, K., Zygmunt, T., Torres-Vazquez, J., Evans*, T., and Hla*, T. (2013). Sphingosine-1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning. J. Biol. Chem. 288: 2143-2156.
Berman, N., Lectura, M., Thurman, J., Raff, A., Melamed, M.L., Reinecke, J., Quan, Z., Evans, T., Meyer, T.W., and Hostetter, T.H. (2013). A Zebrafish Model for Uremic Toxicity: Role of the Complement Pathway. Blood Purification. 35:265-269.
Turbendian, H.K., Gordillo, M., Tsai, S.-Y., Lu, J., Kang, G., Liu, T.-C., Tang, A., Liu, S., Fishman, G.I., and Evans, T. (2013). GATA factors efficiently direct cardiac fate from ESCs. Development. 140: 1639-1644.
Goldman, O., Han, S., Sourrisseau, M., Dziedzic, N., Hamou, W., Corneo, B., D'Souza, S., Sato, T., Kotton, D.N., Bissig, K.-K., Kalir, T., Jacobs, A., Evans, T., Evans, M.J., and Gouon-Evans, V. (2013). KDR (VEGFR2) identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell. 12: 748-760.
Choudhuri, A., Maitra, U., and Evans, T. (2013). Translation initiation factor eIF3h targets specific transcipts to polysomes during embryogenesis. Proc. Natl. Acad. Sci. USA. 110: 9818-9823.
Gupta, V., Gemberling, M., Karra, R., Rosenfeld, G.E., Evans, T., and Poss, K.D. (2013). An Injury-Responsive Gata4 Program Shapes the Zebrafish Cardiac Ventricle. Current Biology. 23: 1221-1227.
Kumar, R., DiMenna, L., Schrode, N., Liu, T.-C., Franck, P., Munoz-Descalzo, S., Hadjantonakis, A.-K, Zarrin, A.A., Chaudhuri, J., Elemento, O., and Evans, T. (2013). AID Stabilizes Stem Cell Phenotype by Removing Epigenetic Memory of Pluripotency Genes. Nature. 500: 89-92.
Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T. (2013). Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis. Dev. Biol. 381: 389-400.
Novikov, N. and Evans, T. (2013). Tmem88a Mediates GATA-dependent Specification of Cardiomyocyte Progenitors by Restricting WNT Signaling. Development. 40: 3787-3798.
2012
Das, B.C., Tang, X.-Y., and Evans, T. (2012). Design and Synthesis of Boron Containing Potential pan-RAR Inverse Agonists. Tetrahedron Lett. 53: 1316-1318. PMID: 23180890.
Xu, C., Fan, Z.P., Muller, P., Fogley, R., DiBiase, A., Trompouki, E., Unternaehrer, J., Xiong, F., Torregroza, I., Evans, T., Megason, S.G., Daley, G.Q., Schier, A.F., Young, R.A., and Zon, L.I. (2012). Nanog Regulates Endoderm Formation through the mxtx2-Nodal Pathway. Dev. Cell. 22: 625-638. PMID: 22421047.
Jung, B., Obinata, H., Galvani, S., Mendelson, K., Ding, B., Skoura, A., Kinzel, B., Brinkmann, V., Rafii, S., Evans, T., and Hla T. (2012). Flow-regulated Intravascular S1P Signaling Sustains Angiogenesis. Dev. Cell. 23: 600-610. PMID: 22975328.
Torregroza, I., Holtzinger, A., Mendelson K., Liu, T.-C., Hla, T., and Evans, T. (2012). Regulation of a Vascular Plexus by gata4 is Mediated in Zebrafish through the Chemokine sdf1a. PLoS ONE. 7: e46844. PMID: 23056483.
Xu, C., Fan, Z.P., Muller, P., Fogley, R., DiBiase, A., Trompouki, E., Unternaehrer, J., Xiong, F., Torregroza, I., Evans, T., Megason, S.G., Daley, G.Q., Schier, A.F., Young, R.A., and Zon, L.I. (2012). Nanog Regulates Endoderm Formation through the mxtx2-Nodal Pathway. Dev. Cell. 22: 625-638. PMID: 22421047.
Jung, B., Obinata, H., Galvani, S., Mendelson, K., Ding, B., Skoura, A., Kinzel, B., Brinkmann, V., Rafii, S., Evans, T., and Hla T. (2012). Flow-regulated Intravascular S1P Signaling Sustains Angiogenesis. Dev. Cell. 23: 600-610. PMID: 22975328.
Torregroza, I., Holtzinger, A., Mendelson K., Liu, T.-C., Hla, T., and Evans, T. (2012). Regulation of a Vascular Plexus by gata4 is Mediated in Zebrafish through the Chemokine sdf1a. PLoS ONE. 7: e46844. PMID: 23056483.
2011
Sedletcaia, A. and Evans, T. (2011). Heart Chamber Size in Zebrafish is Regulated Redundantly by Duplicated Tbx2 Genes. Dev. Dyn. 240: 1548-1557. PMID: 21448936.
Cook, B., Liu, S. and Evans, T. (2011). Smad1 Signaling Restricts Hematopoietic Potential after Promoting Hemangioblast Expansion. Blood. 117: 6489-6497. PMID: 21515822.
Zhong, Y., Wu, Y., Liu, R., Li, Z., Chen, Y., Evans, T., Chuang, P., Das, B., and Je, J.C. (2011). Novel Retinoic Acid Receptor Alpha Agonists for Treatment of Kidney Disease. PLoS One. 6:e27945. PMID: 22125642.
Das, B.C., Tang, X.-Y., Sanyal, S., Mohapatra, S., Rogler, P., Nayak, S., and Evans, T. (2011). Design and Synthesis of 3,5-Disubstituted -1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist. Tetrahedron Lett. 52: 2433-2435. PMID: 21765558.
Cook, B., Liu, S. and Evans, T. (2011). Smad1 Signaling Restricts Hematopoietic Potential after Promoting Hemangioblast Expansion. Blood. 117: 6489-6497. PMID: 21515822.
Zhong, Y., Wu, Y., Liu, R., Li, Z., Chen, Y., Evans, T., Chuang, P., Das, B., and Je, J.C. (2011). Novel Retinoic Acid Receptor Alpha Agonists for Treatment of Kidney Disease. PLoS One. 6:e27945. PMID: 22125642.
Das, B.C., Tang, X.-Y., Sanyal, S., Mohapatra, S., Rogler, P., Nayak, S., and Evans, T. (2011). Design and Synthesis of 3,5-Disubstituted -1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist. Tetrahedron Lett. 52: 2433-2435. PMID: 21765558.