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Todd Evans Laboratory
Weill Cornell Department of Surgery
2017
Guo M, Zhang T, Dong X, Xiang JZ, Lei M, Evans T, Graumann J, Chen S. (2017). Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E. www.ncbi.nlm.nih.gov/pubmed/28538172
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Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D. (2017). Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. www.ncbi.nlm.nih.gov/pubmed/28196600

Tsai SY, Chen S, Evans T. Efficient Generation of Cardiac Purkinje-like Cells from Embryonic Stem Cells by Activating cAMP Signaling. www.ncbi.nlm.nih.gov/pubmed/28152183
2016
Zeng H, Guo M, Zhou T, Tan L, Chong CN, Zhang T, Dong X, Xiang JZ, Yu AS, Yue L, Qi Q, Evans T, Graumann J, Chen S. An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery. www.ncbi.nlm.nih.gov/pubmed/27524441

Simsek, S., Zhou, T., Robinson, C.L., Tsai, S.-Y., Lin, X., Hon, J., Evans, T., and Chen, S. (2016). Modeling Cystic Fibrosis using PSC-derived Human Pancreatic Ductal Epithelial Cells. www.ncbi.nlm.nih.gov/pubmed/27034411
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Feng, L., Cook, B.D., Tsai, S.-Y., Zhou, T., LaFlamme, B., Evans*, T., and Chen*, S. (2016). Discovery of a Small Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation. www.ncbi.nlm.nih.gov/pubmed/27210748


2015

Gordillo, M., Evans, T., and Gouon-Evans, V. (2015). Orchestrating Liver Development. Development. 142(12):2094-2108

Tsai SY., Maass K., Lu J., Fishman G.I., Chen S., Evans T. (2015). Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling.  Stem Cell Reports. 4(6):1089-1102

Mendelson K., Lan Y., Hla T., Evans T. (2015). Maternal or zygotic sphingosine kinase is required to regulate zebrafish cardiogenesis. Dev Dyn. 244(8):948-954

Li C., Lan Y., Schwartz-Orbach L., Korol E., Tahiliani M., Evans T., Goll M.G. (2015). Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell Rep. 12(7):1133-1143

Sundaravel, S., Duggan, R., Bhagat, T.D., Ebenezer, D., Liu, H., Yu, Y., Bartenstein, M., Unnikrishnan, M., Karmakar, S., Liu, T.-C., Torregroza, I., Quenon, T., Anastasi, J., McGraw, K., Pellagatti, A., Boultwood, J., Yajnik, V., Artz, A., Le Beau, M.M., Steidl, U., List, A., Evans*, T., Verma*, A., and Wickrema*, A. (2015). Reduced DOCK4 Expression Leads to Erythroid Dysplasia in Myelodysplastic  Syndromes. Proc. Natl. Acad. Sci. USA. 112: E6359-6368

Kumar, R. and Evans, T. (2015). Haematopoiesis (version 4). Encyclopedia of Life Sciences, Nature Publishing Group, London. www.els.com.

2014

Mendelson, K., Evans, T., and Hla, T. (2014). Sphingosine-1-phosphate Signaling in Development. Development. 141: 5-9.

Lundquist, M.R., Storaska, A., Liu, T.-C., Larsen, S.D., Evans, T., Neubig, R.R., and Jaffrey, S. (2014). Redox Modification of Nuclear Actin by MICAL-2 Regulates SRF Signaling. Cell. 156: 563-576.

Li, X., Lu, Y.-C., Dai, K., Torregroza, I., Hla*, T., and Evans*, T. (2014). Elavl1a Regulates Zebrafish Erythropoiesis via Post-transcriptional Control of gata1. Blood. 123: 1384-1392.

Das, B.C., Thapa, P., Karki, R., Das, S., Mahapatra, S., Liu, T.-C., Torregroza, I., Wallace, D.P., Kambhampati, S., Van Veldhuizen, P., Verma, A., Ray, S.K., and Evans, T. (2014). Retinoic Acid Signaling Pathways in Development and Diseases. Bioorg. Med. Chem. 22: 673-683.

Kleiman, D.A., Beninato T., Sultan, S., Crowley, M.J., Finnerty, B., Kumar, R., Panarelli, N.C., Liu, Y.-F., Lieberman, M.D., Seandel, M., Evans, T., Elemento, O., Zarnegar, R., and Fahey, T.J.III. (2014). Silencing of UCHL1 by CpG Promoter Hypermethylation is Associated With Metastatic Gastroenteropancreatic Well-Differentiated Neuroendocrine (Carcinoid) Tumors. Annals of Surg. Oncol. Suppl 4: 672-679. 

Kumar, R., DiMenna, L.J., Chaudhuri, J., and Evans, T. (2014). Biological Function of Activation-Induced Cytidine Deaminase (AID). Biomed. J.  37: 269-283.

Kumar, R. and Evans, T. (2014). Control of Epigenetic Memory and Pluripotency by DNA Methylation. Cell Biology: Research & Therapy. S1. doi:10.4172/2324-9293.S1-002.

Cook, B.D. and Evans, T. (2014). BMP Signaling Balances Murine Myeloid Potential Through SMAD-independent p38MAPK and NOTCH Pathways. Blood. 124: 393-402. 

2013

Das B.C., McCormick L., Thapa P., Karki R., Evans T. (2013). Use of zebrafish in chemical biology and drug discovery. (2013) Future Med. Chem. 5(17):2103-16

Das B.C., Tang X.Y., Rogler P., Evans T. (2013). Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs. Tetrahedron Lett. 53(31):3947-3950.

Chang, S.-H., Lu, Y.-C., Li, X., Hsieh, W.-Y., Xiong, Y., Ghosh, M., Evans, T., Elemento, O., and Hla, T. (2013). The RNA-binding protein HuR antagonizes miR-200b repression to regulate VEGF-A expression and angiogenesis . J. Biol. Chem. 288: 4908-4921.

Mendelson, K., Zygmunt, T., Torres-Vazquez, J., Evans*, T., and Hla*, T. (2013). Sphingosine-1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning. J. Biol. Chem. 288: 2143-2156.

Berman, N., Lectura, M., Thurman, J., Raff, A., Melamed, M.L., Reinecke, J., Quan, Z., Evans, T., Meyer, T.W., and Hostetter, T.H. (2013). A Zebrafish Model for Uremic Toxicity: Role of the Complement Pathway. Blood Purification. 35:265-269.

Turbendian, H.K., Gordillo, M., Tsai, S.-Y., Lu, J., Kang, G., Liu, T.-C., Tang, A., Liu, S., Fishman, G.I., and Evans, T. (2013). GATA factors efficiently direct cardiac fate from ESCs. Development. 140: 1639-1644.

Goldman, O., Han, S., Sourrisseau, M., Dziedzic, N., Hamou, W., Corneo, B., D'Souza, S., Sato, T., Kotton, D.N., Bissig, K.-K., Kalir, T., Jacobs, A., Evans, T., Evans, M.J., and Gouon-Evans, V. (2013). KDR (VEGFR2) identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell. 12: 748-760.

Choudhuri, A., Maitra, U., and Evans, T. (2013). Translation initiation factor eIF3h targets specific transcipts to polysomes during embryogenesis. Proc. Natl. Acad. Sci. USA. 110: 9818-9823. 

Gupta, V., Gemberling, M., Karra, R., Rosenfeld, G.E., Evans, T., and Poss, K.D. (2013). An Injury-Responsive Gata4 Program Shapes the Zebrafish Cardiac Ventricle. Current Biology. 23: 1221-1227.

Kumar, R., DiMenna, L., Schrode, N., Liu, T.-C., Franck, P., Munoz-Descalzo, S., Hadjantonakis, A.-K, Zarrin, A.A., Chaudhuri, J., Elemento, O., and Evans, T. (2013). AID Stabilizes Stem Cell Phenotype by Removing Epigenetic Memory of Pluripotency Genes. Nature. 500: 89-92.

Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T. (2013). Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis. Dev. Biol. 381: 389-400.

Novikov, N. and Evans, T. (2013). Tmem88a Mediates GATA-dependent Specification of Cardiomyocyte Progenitors by Restricting WNT Signaling. Development. 40: 3787-3798.

2012

Das, B.C., Tang, X.-Y., and Evans, T. (2012). Design and Synthesis of Boron Containing Potential pan-RAR Inverse Agonists. Tetrahedron Lett. 53: 1316-1318. PMID: 23180890. 

Xu, C., Fan, Z.P., Muller, P., Fogley, R., DiBiase, A., Trompouki, E., Unternaehrer, J., Xiong, F., Torregroza, I., Evans, T., Megason, S.G., Daley, G.Q., Schier, A.F., Young, R.A., and Zon, L.I. (2012). Nanog Regulates Endoderm Formation through the mxtx2-Nodal Pathway. Dev. Cell. 22: 625-638. PMID: 22421047. 

Jung, B., Obinata, H., Galvani, S., Mendelson, K., Ding, B., Skoura, A., Kinzel, B., Brinkmann, V., Rafii, S., Evans, T., and Hla T. (2012). Flow-regulated Intravascular S1P Signaling Sustains Angiogenesis. Dev. Cell. 23: 600-610. PMID: 22975328. 

Torregroza, I., Holtzinger, A., Mendelson K., Liu, T.-C., Hla, T., and Evans, T. (2012). Regulation of a Vascular Plexus by gata4 is Mediated in Zebrafish through the Chemokine sdf1a. PLoS ONE. 7: e46844. PMID: 23056483.

2011

Sedletcaia, A. and Evans, T. (2011). Heart Chamber Size in Zebrafish is Regulated Redundantly by Duplicated Tbx2 Genes. Dev. Dyn. 240: 1548-1557. PMID: 21448936.

Cook, B., Liu, S. and Evans, T. (2011). Smad1 Signaling Restricts Hematopoietic Potential after Promoting Hemangioblast Expansion. Blood. 117: 6489-6497. PMID: 21515822. 

Zhong, Y., Wu, Y., Liu, R., Li, Z., Chen, Y., Evans, T., Chuang, P., Das, B., and Je, J.C. (2011). Novel Retinoic Acid Receptor Alpha Agonists for Treatment of Kidney Disease. PLoS One. 6:e27945. PMID: 22125642. 

Das, B.C., Tang, X.-Y., Sanyal, S., Mohapatra, S., Rogler, P., Nayak, S., and Evans, T. (2011). Design and Synthesis of 3,5-Disubstituted -1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist. Tetrahedron Lett. 52: 2433-2435. PMID: 21765558.
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